Ndi Zithunzi Ziti Zomwe Zimakhala Zothandiza Kwambiri Kuzindikira Kubwereza Kwazachilengedwe kwa Khansa ya Prostate: PET/CT kapena mpMRI?

Malinga ndi kafukufuku waposachedwa wa meta, positron emission tomography/computed tomography (PET/CT) ndi multi-parameter magnetic resonance imaging (mpMRI) imaperekanso ziwonetsero zofanana pozindikira khansa ya prostate (PCa) kuyambiranso.

Ofufuzawo adapeza kuti prostate specific membrane antigen (PSMA) PET / CT inali ndi chiwopsezo chonse cha 69% pakuyambiranso khansa ya prostate, poyerekeza ndi 70 peresenti ya mpMRI.

"Kwa [kuyambiranso kwa biochemical], njira zonsezi zimagwira ntchito. Zotsatira zathu zimasonyeza kuti palibe kusiyana kwakukulu pakati pa DR (chiwerengero chozindikiritsa) pakati pa njira ziwiri zowonetsera, ndipo mpMRI imakhala yotsika mtengo pamene ikusunga DR yemweyo, "analemba wolemba nawo kafukufuku L. Xu, wogwirizana ndi School of School of Mankhwala. Hunan University of Traditional Chinese Medicine, Hunan, China ndi anzawo.

Kwa PCa yobwerezabwereza, olemba kafukufuku adanena kuti DR On mpMRI inali 10% yapamwamba (62% vs. 52%). Ofufuzawo adapezanso kuti PSMA PET / CT idawonetsa kusintha kwa 18% ku DR Pozindikira ma lymph node metastasis (50% ndi 32%, motsatana). Komabe, palibe zomwe anapezazo zinali zofunikira kwambiri, olemba maphunzirowo adanena.

Ofufuzawo amakhulupirira kuti kukhudzidwa kwakukulu ndi kutsimikizika kungapereke PSMA PET / CT mwayi pa PCa staging ndikuwona zilonda zazing'ono, komanso amavomereza kuti kupezeka kwa njirayo ndi nkhani. Multi-parameter MRI ingakhale yothandiza pozindikira kubwereza kwa m'deralo komanso PCa yofunika kwambiri, koma olemba kafukufuku amavomereza kuti interobserver heterogeneity ikhoza kukhala vuto ndi mpMRI.

Komabe, zotsatira zonse za meta-analysis zimasonyeza kuti njira zonsezi zili ndi gawo pofufuza PCa BCR, ndikulozera ku maphunziro omwe akuyembekezera mtsogolo omwe angapereke momveka bwino pankhaniyi.

Xu ndi anzake adatsindika kwambiri zotsatira za kafukufuku pazochitika zachipatala. Iwo adawonetsa kuti mphamvu zofananira zowunikira za PSMA PET / CT ndi mpMRI zikuwonetsa mphamvu za njira zonsezi pozindikira BCR kwa odwala PCa. Komabe, iwo anagogomezera kufunika kwa kafukufuku wowonjezereka kuti awone kukhoza, kupezeka, ndi kutsika mtengo kwa njira zojambula zithunzizi.

Pokambirana zoperewera za phunziroli, olembawo adavomereza kuti kukula kwachitsanzo chaching'ono cha odwala 290 chinali chifukwa cha kuyang'ana kwawo pakufufuza kafukufuku woyerekeza kuti azindikire BCR mkati mwa magulu a odwala omwewo. Iwo adawonetsanso kuthekera kwa kukondera pazotsatira chifukwa chamitundu yosiyanasiyana yojambula komanso mawonekedwe a odwala pamaphunziro asanu ndi limodzi omwe adawunikiranso.

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Ndi chitukuko chaukadaulo wojambula zamankhwala, pamatuluka makampani ambiri omwe amatha kupereka zinthu zojambulira, monga majekeseni ndi ma syringe.LnkMedluso lachipatala ndi chimodzi mwa izo. Timapereka mbiri yonse yazinthu zothandizira zowunikira:CT injector imodzi,CT double mutu jekeseni,MRI jekesenindiDSA high pressure jekeseni. Amagwira ntchito bwino ndi mitundu yosiyanasiyana ya scanner ya CT / MRI monga GE, Philips, Siemens. Kupatula jekeseni, timaperekanso syringe ndi chubu chogwiritsidwa ntchito pamitundu yosiyanasiyana ya jakisoni monga Medrad/Bayer, Mallinckrodt/Guerbet, Nemoto, Medtron, Ulrich.
Zotsatirazi ndizo mphamvu zathu zazikulu: nthawi yobereka mofulumira; Ziyeneretso zonse za certification, zaka zambiri zachidziwitso chotumiza kunja, njira yabwino yoyendera bwino, zinthu zogwira ntchito mokwanira, tikulandila mwachikondi kufunsa kwanu.